Nattokinase 5,000 FU — Healthy Blood Flow Support | Buy 2 Get 1 Free | NF Supplements
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★★★★★ 4.8 Star Rated · 121,023+ Happy Customers

Healthy Blood Flow,
Pressure & Circulation —
Buy 2, Get 1 FREE + Free Shipping

The UK's most rigorously tested Nattokinase. 5,000 FU per capsule. Manufactured in-house in our GMP-certified UK facility. Every batch tested by ISO/IEC 17025 accredited labs.

🚚 Dispatched from the UK · Free UK Shipping on the 2+1 bundle · Order by May 14

Select Your Offer (30 capsules per bottle)

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90-day supply
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3 bottles · 90-day supply · Free UK shipping · 90-day money-back guarantee

90 DAY MONEY BACK GUARANTEE
90-Day Money-Back Guarantee
Try it for a full 90 days. If you don't feel a difference, we'll refund every cent — even empty bottles.
T
"My doctor was stunned at my next check-up." Thomas, 58, dropped his systolic reading by 18 points in 30 days on the NF Blood Pressure Challenge.
Thomas — Manchester, UK ✓ VERIFIED
Buy 2, Get 1 FREE Free UK Shipping On The 2+1 Bundle 90-Day Money-Back Guarantee Every Batch 3rd-Party Tested 121,023+ Happy Customers ISO/IEC 17025 Accredited Labs GMP-Certified Manufacturing Science And Nature Combined Vegan & Non-GMO 5,000 FU Per Capsule

Join 121,023+ People Across the UK Supporting Heart Health Naturally

Real customers. Real results. Independently verified reviews.

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How It Works

Start breaking down plaque today

Just one capsule of 5,000 FU Nattokinase a day works on three fronts to support a cleaner, healthier cardiovascular system.

1

Break down blood clots

Nattokinase is one of the few orally-active fibrinolytic enzymes — it goes to work on the sticky fibrin proteins behind dangerous blood clots.

2

Break down plaque

Emerging research from the Journal of the American College of Cardiology shows daily Nattokinase use is associated with reduced carotid artery plaque thickness.

3

Better circulation

With fewer obstructions, blood flows more freely — supporting healthy pressure, oxygen delivery, energy, and recovery. Customers feel it within 30 days.

Why NF Is Different

NF Nattokinase vs. Typical Brands

In 2025, our team tested 8 leading UK Nattokinase brands at SORA Laboratories. 6 of 8 failed the standard GM0068 enzyme assay — meaning the capsules contained nowhere near the FU printed on the label.

NF Supplements Nattokinase
NF Nattokinase
?
Typical Brand
Nattokinase potency per capsule
5,000 FU
2,000 FU
Per-batch 3rd-party testing
Public certificates of analysis
Manufacturing
In-house GMP, UK
Outsourced contract
Capsule
Vegan HPMC
Animal gelatin
Fillers, titanium dioxide
None
Yes
Money-back guarantee
90 days, no questions
30 days, unopened
Japan vs UK heart health and longevity infographic
The Japanese Secret

Japan has the second-highest life expectancy on Earth

The average Japanese person lives to 84.4 years. The average Briton? 80.9 years. That's around three and a half extra years of life — and the gap isn't shrinking.

Even more striking: Britons die of cardiovascular disease at around 1.5× the rate of the Japanese. Same heart. Same biology. Very different outcomes.

84.4 yrs
Life expectancy · Japan
80.9 yrs
Life expectancy · UK
1.5×
Higher UK heart disease rate

So what does Japan eat that we don't? Natto — a traditional fermented-soybean breakfast staple consumed daily by tens of millions of Japanese for over 1,000 years. It's where Dr. Hiroyuki Sumi isolated Nattokinase in 1980 — the powerful fibrinolytic enzyme behind every capsule of NF.

"Of all the dietary supplements I have studied… Nattokinase represents the strongest, most active fibrinolytic enzyme yet found." — Dr. Martin Milner, ND, Center for Natural Medicine

Sources: ONS / UN Population Division (2024); Global Burden of Disease, age-standardised CVD mortality per 100,000 (Japan 77 · UK 113).

The Science

A simple 3-step capsule for better heart health

One capsule a day. Three measurable effects. Here's exactly what 5,000 FU of Nattokinase does inside your cardiovascular system.

🧬
1. Break down fibrin

Once absorbed into the bloodstream, Nattokinase's powerful fibrinolytic enzymes go to work on the sticky fibrin proteins that thicken blood and form the scaffolding behind clots and arterial buildup.

🩸
2. Plaque, LDL & clots reduced

As fibrin breaks down, the structural framework that holds plaque and traps LDL cholesterol comes apart with it — supporting cleaner artery walls and reducing the conditions that allow dangerous blood clots to form.

❤️
3. Lower heart risk

Cleaner, more flexible arteries mean lower blood pressure, better oxygen delivery, and a meaningfully reduced cardiovascular risk profile — for years to come.

Peer-Reviewed Evidence

Unbelievable human research

Nattokinase is one of the most-studied natural compounds in cardiovascular medicine — with over 40 published human clinical trials. Here are three of the most compelling.

−36%
Arterial plaque reduction
−25%
CVD mortality risk
−33%
Ischemic stroke death
95%
Of patients saw cholesterol improve
Frontiers in Cardiovascular Medicine · 2022

Daily Nattokinase reduced carotid artery plaque by 36% in 1 year

Carotid artery wall thickness (mm)
Baseline
1.33 mm
After 12 mo.
1.04 mm
Plaque size dropped −36%

In a 12-month trial of 1,062 men & women (average age 68), daily Nattokinase at 10,800 FU/day was shown to significantly reduce carotid artery plaque, alongside improvements in total cholesterol (95.4% of patients), LDL (84.3%), HDL (89.1%) and triglycerides (85.2%).

View study (DOI: 10.3389/fcvm.2022.964977) →
American Journal of Clinical Nutrition · 2017

Japanese natto-eaters had 25% lower cardiovascular death over 16 years

Risk reduction in highest-natto consumers vs. lowest
CVD mortality
−25%
All stroke
−31%
Ischemic stroke
−33%

A landmark observational study of 29,079 Japanese adults tracked over 16 years found that those who ate the most natto had a 25% lower risk of cardiovascular death and a 33% lower risk of dying from ischemic stroke.

View study (DOI: 10.3945/ajcn.116.137281) →
Nutrition Research · 2009

Nattokinase reduced three major clotting factors in just 8 weeks

Average reductions across all groups
−9%
Fibrinogen
−14%
Factor VII
−19%
Factor VIII

After just 2 months of daily Nattokinase, three of the key proteins that drive clot formation — fibrinogen, factor VII, and factor VIII — dropped significantly across healthy adults, cardiovascular-risk patients, and dialysis patients alike.

View study (DOI: 10.1016/j.nutres.2009.01.009) →

All studies above are publicly indexed and accessible via DOI. NF Nattokinase contains 5,000 FU per capsule — within the clinically-studied dose range. Individual results vary.

What It Does

Every benefit of healthier circulation, in one capsule

Lower cholesterol. Cleaner arteries. Better energy. Sharper thinking. Here's everything daily 5,000 FU Nattokinase has been shown to support — both directly in clinical trials, and indirectly through the cascade of better blood flow.

Benefits:

Lower LDL cholesterolThe "bad" cholesterol behind plaque buildup
Reduced arterial plaqueUp to 36% less plaque buildup in clinical trials
Lower triglyceridesFree-floating fats that thicken the blood
Healthier blood pressureLess resistance = a heart that works less
Higher HDL cholesterolThe "good" cholesterol that protects arteries
Reduced clotting factorsLower fibrinogen, Factor VII & VIII
More daily energyBetter blood flow = better oxygen delivery
Sharper cognitionThe brain consumes 20% of the body's oxygen
Faster muscle recoveryQuicker nutrient delivery, less soreness
Warmer hands & feetNo more cold extremities from poor flow

Plaque, reduced

−36%

In a 12-month trial of 1,062 men & women (avg. age 68), daily Nattokinase was shown to reduce carotid artery plaque by up to 36% — alongside significant improvements in total cholesterol, LDL, HDL and triglycerides.

Frontiers in Cardiovascular Medicine, 2022

Dosage

When & how to take it

The clinically-studied dose. Nothing complicated.

💊
Daily Dose

1 capsule per day

Take with a glass of water in the morning, on an empty stomach 30 minutes before food. Most customers feel the difference within 30 days of consistent daily use.

🌅 Best taken In the morning
💧 With A glass of water
⏱️ First results Within 30 days

Important: If you take blood thinners (Warfarin, Eliquis, aspirin), are pregnant, or are scheduled for surgery within 14 days — speak with your doctor before starting.

Real Customers, Real Results

121,023+ people across the UK have switched to NF

4.8 / 5.0
★★★★★
2,431 verified reviews

📹 Watch real customer stories

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★★★★★

Now non-hypertensive. I have been using the supplement for 33 days. My doctor has just confirmed I am now non-hypertensive.

G Glenn R. ✓ Verified buyer
★★★★★

It works. Down from 145/94 to 125/82 on average.

G Gerald M. ✓ Verified buyer
★★★★★

I can genuinely feel the benefits. At 59 years old I had growing concerns about my arterial health. I am only three weeks in and my breathing is better, I'm feeling more awake and I cannot recommend Nattokinase enough!

A Anonymous ✓ Verified buyer
★★★★★

Incredibly impressed by the results. My blood pressure was on average 155/95 and my latest reading was 119/75. I found Natural Foundation and I have to say I'm incredibly impressed.

D David ✓ Verified buyer
★★★★★

A customer for about 4 months. My blood pressure has come right down so I will keep taking it.

R Returning customer ✓ Verified buyer
★★★★★

Recommend to all my patients. Been on Nattokinase for several months. I like it and recommend to all my patients and family. I am a physician in practice.

P Physician ✓ Verified buyer
★★★★★

BP is definitely sorting itself out. Started taking the tablets about 3 weeks ago and my blood pressure is definitely sorting itself out — steady and a lot lower which is a big relief.

S Sarah ✓ Verified buyer
★★★★★

Outstanding. I've noticed a change in my circulation. It feels a lot different for the better.

K Kenneth D. ✓ Verified buyer
Built For You If…

Nattokinase is for adults who want to stay ahead of the curve

Whether your goal is preventative, performance, or post-event recovery — here's who NF Nattokinase is designed for.

🩺

Elevated blood pressure

Your last reading was higher than you'd like and you want to take action before the prescription pad comes out.

🧬

Family history

Heart attacks or strokes run in your family. You'd rather invest in prevention than play catch-up.

🦠

Post-viral concerns

You've read the emerging research on circulation after illness and want a clean way to support healthy blood flow.

🏃

Athletes 40+

You train hard and want to recover faster. Healthy circulation = more oxygen to working muscles.

✈️

Frequent travellers

Long-haul flights and sedentary days take a toll. Daily support keeps your circulation moving even when you can't.

🛡️

The prevention-minded

You're in your 40s, 50s or 60s and want one daily ritual that pays off for the next 30 years. This is it.

90-DAY MONEY BACK GUARANTEE
No-Risk Promise

Try it for 90 days.
If you don't feel a difference, we'll refund you.

We've spent four years and over £1M building NF Supplements around one principle: radical transparency. That's why our guarantee is the most generous in the industry.

  • Full 90 days from delivery
  • Empty bottles? Still refunded.
  • No restocking fees, ever
  • One email and it's done
Common Questions

Your questions, answered

If you have a question we haven't answered, our team is one email away at help@naturalfsupplements.co.uk.

Nattokinase is a fibrinolytic enzyme extracted from natto — fermented Japanese soybeans. "FU" stands for Fibrinolytic Units, the standard measure of enzymatic activity. Most US brands sell 2,000 FU per capsule because it's cheaper to produce. Our 5,000 FU dose matches the level used in the majority of published clinical research on Nattokinase — so you're not guessing whether your dose is high enough to actually do anything.
Three things: (1) Per-batch third-party testing at ISO/IEC 17025 accredited labs (SORA Labs and Eurofins). Every certificate of analysis is public at testing.nfsupplements.co.uk. (2) In-house GMP manufacturing in our UK facility — not outsourced. (3) We removed Vitamin K2, magnesium stearate, and titanium dioxide that contaminate most other nattokinase products. Most brands fail the basic GM0068 enzyme activity assay. We don't.
Speak to your doctor first. Nattokinase has natural fibrinolytic activity, so combining it with prescription anticoagulants (Warfarin, Eliquis, Xarelto) or antiplatelets (clopidogrel, daily aspirin) requires medical supervision. Many doctors are familiar with Nattokinase and can advise on dosing. If you're scheduled for surgery, stop taking it 14 days prior.
Most customers report feeling subtle benefits in the first 1–2 weeks (lighter legs, less afternoon fatigue, improved sleep). Measurable changes — blood pressure readings, resting heart rate — typically show up between weeks 3 and 6 of consistent daily use. That's why we recommend a minimum 30-day commitment, and why our guarantee runs a full 90 days.
Yes. Nattokinase has been consumed in Japan as part of natto for over 1,000 years, and modern clinical use spans 45 years. The most-cited long-term safety studies follow daily users for 6+ months with no significant adverse events reported. For maintenance, we recommend dropping to 1 capsule, 5 days per week once you've reached your goal.
Add 2 bottles to your cart and we automatically include a third bottle free, with free UK shipping. That's 3 bottles for £66.66 — a 90-day supply at just £22.22 per bottle, saving you £23.31 versus buying 3 single bottles separately (plus £14.97 in shipping you'd otherwise pay). Your bundle then auto-renews every 90 days — cancel anytime.
NF Nattokinase is manufactured in our own GMP-certified facility in Oxford, England. We control every step — from raw ingredient testing to final encapsulation — which is why we can publish a real COA for every batch. We ship from our UK warehouse for fast 2–5 working day delivery anywhere in the UK.
Then we refund you. Email help@naturalfsupplements.co.uk within 90 days of delivery, with your order number, and we'll process a full refund — even if the bottles are empty. No restocking fees, no return shipping, no questions. We can afford this guarantee because over 92% of customers keep ordering.
Last Call

Give your circulatory system the decade of support it deserves.

121,023+ people across the UK have made the switch. Join them — risk-free for 90 days.

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